Last Updated on April 8, 2026 by Sarah Leadon
This low-carb beef and vegetable casserole is hearty. It’s cheesy and packed with flavor without all the heavy carbs. It’s the perfect weeknight dinner when you want something that’s comforting but still nutritious. The combination of ground beef, fresh vegetables, rich tomato-based sauce, and melty cheese makes this casserole so satisfying.
Ingredients
This beef and vegetable casserole is very easy to make. Here are some of the ingredients you need to make it:
- Cabbage: Green cabbage adds texture. It’s also low-carb and helps keep you fuller longer.
- Mushrooms: They add umami flavor to the casserole. They soak up the sauce’s flavors really well.
- Cauliflower: They are a great low-carb substitute for potatoes.
- Red Onions: Adds sweetness and color.
- Cheese: I used a mix of mozzarella and cheddar, but you can use cheddar, parmesan, or any cheese you’d like.
Scroll down to the recipe card to see the full list of ingredients and measurements.

🥘 Tips 🥘
- Drain the vegetables. Vegetables contain a lot of water. After you sautee them, drain any liquid. If you don’t, the casserole will be watery.
- Use lean ground beef. Fatty beef shrinks more. It releases extra grease, which can make the casserole oily.
- Season in layers. Adding salt and spices at different stages of cooking to build deeper flavor.
- Let it rest. Let the beef and vegetable casserole sit for 10 minutes. It will be easier to serve.
Variations
This casserole is incredibly flexible. Try these swaps:
- Broccoli: Replace the cauliflower or cabbage with broccoli florets.
- Ground turkey or chicken: You can use either to make the meat sauce. It will be lighter and just as flavorful as a beef meat sauce.
- Zucchini or squash: Slice and sauté it with the mushrooms for extra veggies.
- Creamier version: Stir in a ½ cup of heavy cream to the meat sauce before mixing it with the vegetables.
Serving Suggestions
This beef and vegetable casserole is filling on its own, but you can pair it with:
- A simple green salad
- Roasted asparagus or green beans
- Cauliflower mash
- Keto garlic bread
- A dollop of sour cream


How To Store Beef And Vegetable Casserole
You can store leftover beef and vegetable casserole in an airtight container in the fridge for 4 days. You can also freeze it for 2 months. Just make sure you store it in a freezer-safe container.
You have two options for reheating this casserole. You can reheat it in the microwave in 1-minute intervals until it’s warm. You can also reheat it in the oven at 325°F (162°C) for 15-25 minutes.
👩🏾🍳Pro Tip👩🏾🍳
If you are feeding people that don’t like leftovers, refresh the casserole. Scoop the casserole into ramekins or small oven‑safe skillets. Add a spoonful of marinara sauce to moisten it and top with extra cheese. Bake at 325°F (162°C) for 20–30 minutes until bubbly. This trick makes the casserole taste freshly made, and no one will know it’s leftovers.
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